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Cat scratch disease

Definition

Cat scratch disease is an infectious illness caused by the bacteriaBartonella, believed to be transmitted by cat scratches, bites, or exposure to cat saliva. This leads to swelling of the lymph nodes (lymphadenopathy) near the site of the scratch or bite.

Alternative Names

CSD; Cat scratch fever; Bartonellosis

Causes

Cat scratch disease is caused by Bartonella henselae. The disease is spread through contact with an infected cat, as a result of a cat bite or scratch, or contact with cat saliva on broken skin or the conjunctiva of the eye.

Lymph node swelling begins about 2 to 3 weeks after exposure and may persist for months. Swelling may occur at the site of the initial infection followed by enlarged lymph nodes along the lymph drainage route from the injury site.

Occasionally, nodes may form a fistula through the skin and drain. Cat scratch disease is one of the common causes of chronic lymph node swelling in children. Until now, the disease often went unrecognized because of the difficulty in testing.

Recently however, the Bartonella henselae IFA test was shown to be highly sensitive and specific for the detection of infection caused by Bartonella henselae and for the diagnosis of cat scratch disease.


Review Date: 1/16/2004
Reviewed By: Daniel Levy, M.D., Ph.D., Infectious Diseases, Greater Baltimore Medical Center, Baltimore, MD. Review provided by VeriMed Healthcare Network.
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