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Testicular failure

Definition

Testicular failure is the inability of thetesticles to produce sperm or male hormones.

Alternative Names

Primary hypogonadism - male

Causes

Causes of testicular failure include chromosomal abnormalities, testicular torsion, direct trauma to the testicles, diseases that affect the testicle (such as mumps, orchitis [inflammation of the testes], and testicular cancer), and a variety of drugs. The condition is uncommon.

Increased risk is associated with activities that may cause constant, low-level trauma to the scrotum (such as riding a motorcycle) or frequent administration of a drug known to affect testicular function (such as heavy marijuana use or taking some prescription medications). Men who had undescended testicles at birth are at higher risk.


Review Date: 10/6/2003
Reviewed By: Tarun Jain, M.D., Endocrinology & Infertility Division, Brigham and Women's Hospital, Boston, MA. Review provided by VeriMed Healthcare Network
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