Metabolic acidosis

Definition

Metabolic acidosis is a disturbance of the body acid-base balance in which there is excessive acidity of the blood. Metabolic acidosis can occur as a result of many different conditions, such as kidney failure, poisoning, diabetic ketoacidosis (DKA), and shock.

Many of these conditions are life-threatening. If severe, metabolic acidosis may lead to shock or death. In some situations, metabolic acidosis can be a mild, chronic condition.

Alternative Names

Acidosis - metabolic

Causes

Many different diseases and medical conditions can lead to metabolic acidosis. For example, diabetes mellitus type 1 (juvenile diabetes), when out of control, leads to diabetic ketoacidosis.

Kidney failure is another important cause of metabolic acidosis. Ingestion of toxic substances, such as antifreeze or excessive amounts of aspirin, can also lead to metabolic acidosis. Shock (extremely low blood pressure) can also cause this condition.