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Chemical pneumonitis

Definition

Chemical pneumonitis is an inflammation of the lungs (pneumonitis) orbreathing difficulty caused by inhalation of noxious chemicals.

Causes

Many household and industrial chemicals are capable of producing both an acute and a chronic form of inflammation in the lung. Acute chemical pneumonitis causes swelling of the lung tissue, movement of fluid into the air spaces in the lung, and less ability to absorb oxygen and get rid of carbon dioxide. In severe cases, death may result from lack of oxygen reaching the tissues (hypoxia).

Chlorine gas is one of the most irritating commonly inhaled substance. Exposure to dangerous levels of chlorine gas may occur at home (during use of cleaning materials such as chlorine bleach), in industrial accidents, or near swimming pools. Inhalation of dangerous substances can occur in many different settings, including factories (especially during smelting, welding, or other metal work), the production or use of solvents or pesticides, fires (house fires, wildfires), and the handling of grain.

Chronic chemical pneumonitis can follow low levels of exposure to the lung irritant over extended periods of time. This causes inflammation and may provoke fibrosis (scarring) with decreased oxygen exchange and stiffening of the lung. Unchecked, this condition may ultimately lead to respiratory failure and death.


Review Date: 4/22/2003
Reviewed By: David A. Kaufman, M.D., Pulmonary & Critical Care Medicine, University of Pennsylvania Medical Center, Philadelphia, PA. Review provided by VeriMed Healthcare Network.
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