Glutamic Acid

Glutamic Acid

Other name(s):

a-aminoglutaric acid

Reported uses

Glutamic acid is often used in the treatment of hypochlorhydria and achlorhydria.

Unsubstantiated claims

Please note that this section reports on claims that have NOT yet been substantiated through scientific studies.

Glutamic acid is believed to play a role in the treatment of personality and childhood behavioral disorders, epilepsy, muscular dystrophy, and intellectual disability.

Glutamic acid has sometimes been used in cases of hypoglycemia, a complication resulting from insulin treatment for diabetes.

Recommended intake

Amino acids (AAs), such as glutamic acid, are available as individual AAs or in proprietary AA combinations, as well as part of multi-vitamin formulas, proteins, and food supplements. The forms include tablets, fluids, and powders. However, adequate protein in the diet should provide a sufficient source of all amino acids.

For adults with hypochlorhydria or achlorhydria, the recommended dosage is 500–1000 mg/day orally before meals or food. 

There are no conditions that increase the nutritional requirements for glutamic acid.

Side effects, toxicity, and interactions

The use of a single amino acid supplement may lead to a negative nitrogen balance, decreasing the metabolic efficiency and increasing the workload of the kidneys. In children, taking single amino acid supplements may also harmfully affect growth parameters.

Always avoid taking individual amino acids in high dosage for prolonged periods.

Women who are pregnant or breastfeeding also should not use glutamic acid supplements.

Individuals with some forms of maple syrup urine disease (MSUD), a rare, inherited disorder, should not use glutamic acid supplements.

Systemic acidosis may occur with considerable overdosage. 

Additional information

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