A  A  A   Print
Whooping Cough Vaccination During Pregnancy Seems Safe: Study

Whooping Cough Vaccination During Pregnancy Seems Safe: Study

SATURDAY, May 3, 2014 (HealthDay News) -- Vaccinating pregnant women during their third trimester to prevent tetanus, diphtheria and pertussis in their future offspring appears to be safe for both mother and child, new research suggests.

The findings -- which may provide some reassurance to parents with general concerns about vaccination safety -- are reported in the May 7 issue of the Journal of the American Medical Association.

The new preliminary study explored the safety of the "Tdap" vaccine when offered before birth.

The investigation was prompted by the particular threat to infants posed by pertussis -- commonly known as whooping cough -- a highly contagious and sometimes deadly disease that has recently made a comeback among American children.

About 90 percent of fatal cases of whooping cough occur among children under the age of 6 months, according to background information from the journal.

However, although the disease is preventable if vaccinated against, current recommendations advise that the "DTaP" vaccine -- a different form of the vaccine used to prevent the same conditions -- be offered only to infants at the ages of 2 months, 4 months and 6 months.

This leaves open a potential window of risk between the time of birth and the first dose of DTaP, in which the newborn infant is not protected.

To cope with that window, researchers focused on the notion of vaccinating pregnant women. In theory, this would prompt mothers-to-be into developing pertussis antibodies that would, in turn, protect the fetus and, ultimately, the newborn.

The research team, led by Dr. Flor Munoz, at Baylor College of Medicine in Houston, followed 48 pregnant women. Of these, 33 were given the Tdap vaccine during their third trimester. The other 15 received a placebo (sham) vaccine.

No unexpected adverse reactions were observed among the mothers who were inoculated, or among their children. In addition, growth and development was similar among infants whose mothers were vaccinated during pregnancy compared to those whose mothers were not, according to a journal news release.

Children born to mothers who were vaccinated while pregnant were found to have much higher levels of pertussis antibodies in their systems than children whose mothers weren't -- both at birth and again at age 2 months -- the time of each infant's own first inoculation.

The authors noted that further research will be needed to confirm the safety and effectiveness of Tdap vaccination during pregnancy. The new study findings will also be presented at the annual meeting of the Pediatric Academic Societies, held in Vancouver.

More information

To learn more about the Tdap vaccine, visit the U.S. Centers for Disease Control and Prevention.

SOURCE: Journal of the American Medical Association, news release, May 3, 2014

 
Today's Interactive Tools
Related Items

The third-party content provided in the Health Library of phoebeputney.com is for informational purposes only and is not designed to diagnose or treat a health problem or disease, or replace the professional medical advice you receive from your physician. If you or your child has or suspect you may have a health problem, please consult your primary care physician. If you or your child may have a medical emergency, call your doctor or 911 or other emergency health care provider immediately in the United States or the appropriate health agency of your country. For more information regarding site usage, please visit: Privacy Information, Terms of Use or Disclaimer.

Follow us online:

© 2014 Phoebe Putney Health System  |  417 Third Avenue, Albany, Georgia 31701  |  Telephone 877.312.1167

Phoebe Putney Health System is a network of hospitals, family medicine clinics, rehab facilities, auxiliary services, and medical education training facilities. Founded in 1911,
Phoebe Putney Memorial Hospital (the flagship hospital) is one of Georgia's largest comprehensive regional medical centers. From the beginning, Phoebe's mission and vision
has been to bring the finest medical talent and technology to the citizens of Southwest Georgia, and to serve all citizens of the community regardless of ability to pay.