A  A  A   Print
Fluoxetine; OlanzapineFluoxetine; Olanzapine

Olanzapine, Fluoxetine Hydrochloride Oral capsule

What is this medicine?

FLUOXETINE; OLANZAPINE (floo OX e teen; oh LAN za peen) is used to treat episodes of depression that have not been relieved by the use of other medicines and depression caused by bipolar disorder.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • Alzheimer's disease or dementia

  • bleeding disorders

  • diabetes

  • glaucoma

  • heart disease, irregular heartbeat, or previous heart attack

  • high blood pressure treated with medication

  • kidney disease

  • liver disease

  • low blood pressure

  • low levels of potassium or magnesium in the blood

  • Parkinson's disease

  • receiving electroconvulsive therapy

  • strokes, or mini-strokes called transient ischemic attacks (TIAs)

  • suicidal thoughts, plans, or attempt; a previous suicide attempt by you or a family member

  • an unusual or allergic reaction to fluoxetine, olanzapine, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

Take this medicine by mouth with a glass of water. Follow the directions on the prescription label. You can take this medicine with or without food. Take your doses at regular intervals. Do not take your medicine more often than directed. Do not stop taking this medicine suddenly except upon the advice of your doctor. Stopping this medicine too quickly may cause serious side effects or your condition may worsen.

A special MedGuide will be given to you by the pharmacist with each prescription and refill. Be sure to read this information carefully each time.

Talk to your pediatrician regarding the use of this medicine in children. While this drug may be prescribed for children as young as 10 years of age for selected conditions, precautions do apply.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • other medicines containing fluoxetine or olanzapine, such as Prozac, Sarafem, or Zyprexa

  • cisapride

  • dofetilide

  • dronedarone

  • linezolid

  • MAOIs like Carbex, Eldepryl, Marplan, Nardil, and Parnate

  • methylene blue (injected into a vein)

  • metoclopramide

  • pimozide

  • thioridazine

  • ziprasidone

This medicine may also interact with the following medications:

  • alcohol

  • aspirin or aspirin-like medicines

  • carbamazepine

  • certain medicines for depression, anxiety, or psychotic disturbances

  • certain medicines for migraine headaches like almotriptan, eletriptan, frovatriptan, naratriptan, rizatriptan, sumatriptan, zolmitriptan

  • digoxin

  • diuretics

  • fentanyl

  • flecainide

  • furazolidone

  • isoniazid

  • lithium

  • medicines for high blood pressure

  • medicines for Parkinson's disease

  • medicines for sleep

  • medicines that treat or prevent blood clots like warfarin, enoxaparin, and dalteparin

  • NSAIDs, medicines for pain and inflammation, like ibuprofen or naproxen

  • omeprazole

  • other medicines that prolong the QT interval (cause an abnormal heart rhythm)

  • phenytoin

  • procarbazine

  • propafenone

  • rifampin

  • ritonavir

  • supplements like St. John's wort, kava kava, valerian

  • tramadol

  • tryptophan

  • vinblastine

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Tell your doctor if your symptoms do not get better or if they get worse. Visit your doctor or health care professional for regular checks on your progress. Because it may take several weeks to see the full effects of this medicine, it is important to continue your treatment as prescribed by your doctor.

Patients and their families should watch out for new or worsening thoughts of suicide or depression. Also watch out for sudden changes in feelings such as feeling anxious, agitated, panicky, irritable, hostile, aggressive, impulsive, severely restless, overly excited and hyperactive, or not being able to sleep. If this happens, especially at the beginning of treatment or after a change in dose, call your health care professional.

You may get drowsy or dizzy. Do not drive, use machinery, or do anything that needs mental alertness until you know how this medicine affects you. Do not stand or sit up quickly, especially if you are an older patient. This reduces the risk of dizzy or fainting spells. Alcohol may interfere with the effect of this medicine. Avoid alcoholic drinks.

Your mouth may get dry. Chewing sugarless gum or sucking hard candy, and drinking plenty of water may help. Contact your doctor if the problem does not go away or is severe.

This medicine can reduce the response of your body to heat or cold. Dress warm in cold weather and stay hydrated in hot weather. If possible, avoid extreme temperatures like saunas, hot tubs, very hot or cold showers, or activities that can cause dehydration such as vigorous exercise.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • breathing problems

  • confusion

  • difficulty in speaking or swallowing

  • excessive thirst and/or hunger

  • fast heartbeat

  • fast talking and excited feelings or actions that are out of control

  • fever or chills, sore throat

  • flu-like symptoms

  • frequently needing to urinate

  • muscle spasms or weakness

  • painful or prolonged erections

  • seizures

  • suicidal thoughts or other mood changes

  • swelling of face or legs

  • tremors

  • unusual bleeding or bruising

  • unusually tired or weak

  • vomiting

  • weight gain

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • blurred vision

  • change in sex drive or performance

  • constipation or diarrhea

  • drowsy

  • flushing

  • lowered blood pressure

  • nausea

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

Keep out of the reach of children.

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F). Protect from moisture. Keep container tightly closed. Throw away any unused medicine after the expiration date.


 
Today's Interactive Tools
Related Items

The third-party content provided in the Health Library of phoebeputney.com is for informational purposes only and is not designed to diagnose or treat a health problem or disease, or replace the professional medical advice you receive from your physician. If you or your child has or suspect you may have a health problem, please consult your primary care physician. If you or your child may have a medical emergency, call your doctor or 911 or other emergency health care provider immediately in the United States or the appropriate health agency of your country. For more information regarding site usage, please visit: Privacy Information, Terms of Use or Disclaimer.

Follow us online:

© 2014 Phoebe Putney Health System  |  417 Third Avenue, Albany, Georgia 31701  |  Telephone 877.312.1167

Phoebe Putney Health System is a network of hospitals, family medicine clinics, rehab facilities, auxiliary services, and medical education training facilities. Founded in 1911,
Phoebe Putney Memorial Hospital (the flagship hospital) is one of Georgia's largest comprehensive regional medical centers. From the beginning, Phoebe's mission and vision
has been to bring the finest medical talent and technology to the citizens of Southwest Georgia, and to serve all citizens of the community regardless of ability to pay.