A  A  A   Print
Alteplase, tPAAlteplase, tPA

Alteplase Solution for injection

What is this medicine?

ALTEPLASE (AL te plase) can dissolve blood clots that form in the heart, blood vessels, or lungs after a heart attack. This medicine is also given to improve recovery and decrease the chance of disability in patients having symptoms of a stroke.

This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions.

What should I tell my health care provider before I take this medicine?

They need to know if you have any of these conditions:

  • aneurysm

  • bleeding problems or problems with blood clotting

  • blood vessel disease or damaged blood vessels

  • diabetic retinopathy

  • head injury or tumor

  • high blood pressure

  • infection

  • irregular heartbeats

  • previous stroke

  • recent biopsy or surgery

  • an unusual or allergic reaction to alteplase, other medicines, foods, dyes, or preservatives

  • pregnant or trying to get pregnant

  • breast-feeding

How should I use this medicine?

This medicine is for injection into a vein. It is given by a health care professional in a hospital or clinic setting.

Talk to your pediatrician regarding the use of this medicine in children. Special care may be needed.

Overdosage: If you think you have taken too much of this medicine contact a poison control center or emergency room at once.

NOTE: This medicine is only for you. Do not share this medicine with others.

What if I miss a dose?

This does not apply.

What may interact with this medicine?

Do not take this medicine with any of the following medications:

  • aminocaproic acid

  • aprotinin

  • tranexamic acid

This medicine may also interact with the following medications:

  • antiinflammatory drugs, NSAIDs like ibuprofen

  • aspirin and aspirin-like medicines

  • blood thinners, like warfarin, heparin or enoxaparin

  • dipyridamole

This list may not describe all possible interactions. Give your health care provider a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. Some items may interact with your medicine.

What should I watch for while using this medicine?

Your condition will be monitored carefully while you are receiving this medicine. Follow the advice of your doctor or health care professional exactly. You may need bed rest to minimize the risk of bleeding.

This medicine can make you bleed more easily. This effect can last for several days. Take special care brushing or flossing your teeth.

Do not take aspirin, ibuprofen, or other nonprescription pain relievers during or for several days after alteplase treatment unless otherwise instructed by your doctor or health care professional.

You may feel dizzy or lightheaded. To avoid the risk of dizzy or fainting spells, sit or stand up slowly, especially if you are an older patient.

What side effects may I notice from receiving this medicine?

Side effects that you should report to your doctor or health care professional as soon as possible:

  • allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue

  • blood in the urine, stools, or vomit

  • chest pain or tightness

  • constipation

  • fever

  • severe headache

  • shortness of breath

  • slow or fast heart rate

  • unusual bleeding, bruising, or purple spots on the skin

Side effects that usually do not require medical attention (report to your doctor or health care professional if they continue or are bothersome):

  • dizziness, lightheadedness

  • nausea, vomiting

This list may not describe all possible side effects. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Where should I keep my medicine?

This does not apply. You will not be given this medicine to store at home.


 
Today's Interactive Tools
Related Items

The third-party content provided in the Health Library of phoebeputney.com is for informational purposes only and is not designed to diagnose or treat a health problem or disease, or replace the professional medical advice you receive from your physician. If you or your child has or suspect you may have a health problem, please consult your primary care physician. If you or your child may have a medical emergency, call your doctor or 911 or other emergency health care provider immediately in the United States or the appropriate health agency of your country. For more information regarding site usage, please visit: Privacy Information, Terms of Use or Disclaimer.

Follow us online:

© 2014 Phoebe Putney Health System  |  417 Third Avenue, Albany, Georgia 31701  |  Telephone 877.312.1167

Phoebe Putney Health System is a network of hospitals, family medicine clinics, rehab facilities, auxiliary services, and medical education training facilities. Founded in 1911,
Phoebe Putney Memorial Hospital (the flagship hospital) is one of Georgia's largest comprehensive regional medical centers. From the beginning, Phoebe's mission and vision
has been to bring the finest medical talent and technology to the citizens of Southwest Georgia, and to serve all citizens of the community regardless of ability to pay.